Drugs Reported to Cause Priapism
In one-third of the cases, the cause of priapism is unknown. The remaining cases are caused by an associated condition, including sickle cell disease, pelvic tumors, pelvic infections, leukemia, genital trauma or spinal cord trauma. A variety of medications or recreational drugs also can lead to priapism.
Antidepressants
- Bupropion
- Trazodone
- Fluoxetine
- Sertraline and lithium
Antipsychotics
- Clozapine
Antianxiety Agents
- Hydroxyzine
Psychotropics
- Chlorpromazine
Alpha-adrenergic Blocker
- Prazosin
Hormones
- Gonadotropin-releasing hormone (in hypogonadal men)
- Testosterone
Anticoagulants
- Heparin
- Coumadin
Recreational Drugs
- Cocaine
- Alcohol
UCSF Health medical specialists have reviewed this information. It is for educational purposes only and is not intended to replace the advice of your doctor or other health care provider. We encourage you to discuss any questions or concerns you may have with your provider.